The Third Noble Truth is about letting go of our attachment to desires. Part One of this dharma talk establishes what happens when we use attachment to hang onto our misery and what could happen if we chose to let it go.
There’s pain and pain is inevitable, but misery is a choice.
…Misery is the holding on that arises because of our attachment to the way things are or our resistance to the way things are, wanting them either to become some way or “unbecome” the way they are—that’s actually what we’re talking about when we talk about anguish. I think those things aren’t often separated. So, it’s not the initial experience of, Oh, wow that hurt. It’s the commiserating on the thing in your own mind and carrying it into the next moment.